Subtitle Irreversible
A.2.1.1 Skin corrosion is the production of irreversible damage to the skin; namely, visible necrosis through the epidermis and into the dermis, following the application of a test substance for up to 4 hours. Corrosive reactions are typified by ulcers, bleeding, bloody scabs, and, by the end of observation at 14 days, by discoloration due to blanching of the skin, complete areas of alopecia, and scars. Histopathology should be considered to evaluate questionable lesions.
subtitle Irreversible
A.7.2.3.5 If appropriate information is available it is important to try to determine whether developmental toxicity is due to a specific maternally mediated mechanism or to a non-specific secondary mechanism, like maternal stress and the disruption of homeostasis. Generally, the presence of maternal toxicity should not be used to negate findings of embryo/fetal effects, unless it can be clearly demonstrated that the effects are secondary non-specific effects. This is especially the case when the effects in the offspring are significant, e.g., irreversible effects such as structural malformations. In some situations it is reasonable to assume that reproductive toxicity is due to a secondary consequence of maternal toxicity and discount the effects, for example if the chemical is so toxic that dams fail to thrive and there is severe inanition; they are incapable of nursing pups; or they are prostrate or dying.
A.7.2.4.2 Based on pragmatic observation, it is believed that maternal toxicity may, depending on severity, influence development via non-specific secondary mechanisms, producing effects such as depressed fetal weight, retarded ossification, and possibly resorptions and certain malformations in some strains of certain species. However, the limited numbers of studies which have investigated the relationship between developmental effects and general maternal toxicity have failed to demonstrate a consistent, reproducible relationship across species. Developmental effects which occur even in the presence of maternal toxicity are considered to be evidence of developmental toxicity, unless it can be unequivocally demonstrated on a case by case basis that the developmental effects are secondary to maternal toxicity. Moreover, classification shall be considered where there is a significant toxic effect in the offspring, e.g., irreversible effects such as structural malformations, embryo/fetal lethality, or significant post-natal functional deficiencies.
A.8.1.1 Specific target organ toxicity - single exposure, (STOT-SE) means specific, non-lethal target organ toxicity arising from a single exposure to a chemical. All significant health effects that can impair function, both reversible and irreversible, immediate and/or delayed and not specifically addressed in A.1 to A.7 and A.10 of this Appendix are included. Specific target organ toxicity following repeated exposure is classified in accordance with SPECIFIC TARGET ORGAN TOXICITY - REPEATED EXPOSURE (A.9 of this Appendix) and is therefore not included here.
A.9.1.1 Specific target organ toxicity - repeated exposure (STOT-RE) means specific target organ toxicity arising from repeated exposure to a substance or mixture. All significant health effects that can impair function, both reversible and irreversible, immediate and/or delayed and not specifically addressed in A.1 to A.7 and A.10 of this Appendix are included. Specific target organ toxicity following a single-event exposure is classified in accordance with SPECIFIC TARGET ORGAN TOXICITY - SINGLE EXPOSURE (A.8 of this Appendix) and is therefore not included here.
Researchers used observations to explore coupling between deforestation, surface and vertically-resolved climate, and the potential for irreversible transitions in Amazonian forests. This study found that severe atmospheric desiccation in the southern and eastern Amazon cannot be compensated by enhanced water supplies from the Atlantic Ocean, demonstrating an irreversible transition in the hydrological cycle exacerbated by ongoing deforestation.
A. The director shall adopt rules to establish a hazardous waste management program equivalent to and consistent with the federal hazardous waste regulations promulgated pursuant to subtitle C of the federal act. Federal hazardous waste regulations may be adopted by reference. The director shall not adopt a nonprocedural standard that is more stringent than or conflicts with those found in 40 Code of Federal Regulations parts 260 through 268, 270 through 272, 279 and 124. The director shall not identify a waste as hazardous if not so identified in the federal hazardous waste regulations unless the director finds, based on all the factors in 40 Code of Federal Regulations section 261.11(a)(1), (2), or (3), that the waste may cause or significantly contribute to an increase in serious irreversible or incapacitating reversible illness or pose a substantial present or potential hazard to human health or the environment when it is improperly treated, stored, transported, disposed or otherwise managed.
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Example: "Friedman, in his book The Lexus and the Olive Tree, has mentioned that globalization is inevitable and irreversible, the forward march of technology makes it so. Governments can no longer control the free flow of information. The cell phone and satellite television have reached even the remotest Indonesian village" ("A Critique," 2001, p. A4).
(This is probably not the right place, but perhaps Peter permits me to come to a closure with my previous somewhat sketchy remark)The decoherence solves the problem for all practical purposes, but being within QM it cannot explain the closure of this process namely the irreversible factualization which happens at the moment of registration (which may be done by a machine).
anonymousI cannot speak for Smolin, but I agree with you (see my contribution here before Christine); decoherence leads to a loss of phases for all practical purposes and hence solves the measurement problem fapp. However the event of observation (blackening of a photoplate, click in a counter) is irreversible (factualization) and QM (decoherence is part of QM) is reversible.
N2 - Faced with the increasing and irreversible impacts of climate change, a growing number of public and private stakeholders across vulnerable sectors are engaging in adaptation efforts. However, our knowledge is limited regarding the types of information being demanded in order to track adaptation progress nationally. To address this gap, we conducted a needs assessment of 191 public and private stakeholder organizations. Stakeholder needs are classified into fourteen themes, encompassing measurements in implementation, outcome and learning, data availability and methods, and crosscutting aspects. With approximately half of organizations surveyed expressing a need for adaptation tracking, we conclude that there is significant demand for: 1) translating climate risk data into impacts and damage costs; 2) monitoring institutional and policy coordination and coherence; and 3) evaluating adaptation outputs and outcomes to inform decision-making.
AB - Faced with the increasing and irreversible impacts of climate change, a growing number of public and private stakeholders across vulnerable sectors are engaging in adaptation efforts. However, our knowledge is limited regarding the types of information being demanded in order to track adaptation progress nationally. To address this gap, we conducted a needs assessment of 191 public and private stakeholder organizations. Stakeholder needs are classified into fourteen themes, encompassing measurements in implementation, outcome and learning, data availability and methods, and crosscutting aspects. With approximately half of organizations surveyed expressing a need for adaptation tracking, we conclude that there is significant demand for: 1) translating climate risk data into impacts and damage costs; 2) monitoring institutional and policy coordination and coherence; and 3) evaluating adaptation outputs and outcomes to inform decision-making.
We based our decision on a thorough analysis of the effects to the human environment, including environmental, social, and economic considerations found in the Final EIS. We have evaluated the effects of proposed roads through Izembek Refuge and Izembek Wilderness in numerous analyses since 1960, including the 1985 Comprehensive Conservation Plan and through the completion of the current EIS. We have consistently found that the impacts of building a proposed road on the wildlife resources, habitats, and designated Wilderness would create irreversible change and damage to a unique and ecologically important area, and especially to designated Wilderness. The no action alternative selected in the ROD supports the continued management of the Izembek Refuge consistent with the purposes for which it was established. 041b061a72